Hi All For the sake of completeness I got this to work locally by enabling a couple of repositories. It all worked seamlessly after that for installing R. FROM registry.access.redhat.com/ubi8/ubi RUN yum -y update && yum -y install yum-utils && yum-config-manager --enable rhel-8-for-x86_64-supplementary-rpms && yum-config-manager --enable codeready-builder-for-rhel-8-x86_64-rpms && yum -y install https://dl.fedoraproject.org/pub/epel/epel-release-latest-8.noarch.rpm && yum -y install R-core-devel R-devel R This is on a registered local machine. it can't be built in quay.io like this, and I'm wondering if this also isn't allowed with that ubi8 image in quay.io in a public repository. R is one of the many building blocks we use for genetic analysis, and I'm keen to share information like this. Bryan